Susan Messing's weekly show, where she pairs off with a guest "friend" for an hour of purely improvised comedy, is one of the funniest entertainments in town. Messing is deeply talented: her acting is focused and nuanced, and she's got one of the the sharpest shit-detectors around, allowing her to cut or extend scenes like a good director. She works with a different "friend" at nearly every performance, often for the first time ever, and each prods her in unpredictable ways. But Messing stays on her toes, finding newer and quirkier characters—like a chatty old lady who sings musical numbers and pop songs at work or a wife from a 1940s screwball comedy who encourages her husband to tie her up—and the proportion of what works to what doesn't is a testament to her congeniality, experience, and broad intelligence. Messing was my pick for Best Improviser in the Reader's 2008 Best Of Chicago issue. --Ryan Hubbard